@SwiftOnSecurity Here's how they transport nuclear waste from the sites that produce it to the storage sites.
These TRUPACT containers hold 14 55 gallon drums of waste. They can transport 2-3 on a flatbed along the interstate highways to get from the source to the destination.
The destination is usually the Waste Isolation Pilot Plant, located in New Mexico.
The engineering and testing of the TRUPACT is really interesting. Details here: https://www.wipp.energy.gov/fctshts/TRUwastecontainers.pdf