Muscles grow by increasing the size of their cells, not by increasing the number of cells. In contrast, the cells of the immune system and body mainly increase by reproducing in response to infection.

These cell divisions have a limit. Telomeres, at the end of chromosomes, shorten with each division until the cell stops dividing or dies.

#Covid19 shortens Telomeres. Yes, immune systems will age.
https://mastodon.green/@fitterhappierAJ/109372994883071557

Anthony J Leonardi (@[email protected])

A misanalogy offers a teaching moment Muscles grow by hypertrophy rather than proliferation The cells of your immune system and body predominantly divide in response to infection The divisions have a limit Telomeres shorten after SARS 2 infection Yea, immune systems will age

Mastodon.green
@LeonardiBot this was the exact explanation I’ve needed, for months, regarding why we run out of naive T Cells. I finally get it! Thank you!