Gabriele Pollara

Prokaryotic innate immune sensing of viruses!

When we talk about conserved immune responses, ability to detect viral intracellular infection stretches all the way back to bacteria too...

#immunology #virus #bacteria #phages

https://www.nature.com/articles/s41586-022-05444-z

Direct activation of a bacterial innate immune system by a viral capsid protein - Nature

Genetic, biochemical and structural studies provide insights into the function of Escherichia coli CapRelSJ46 as a fused anti-phage toxin–antitoxin system that binds SECΦ27 Gp57 capsid protein.

Nature
Nov 17, 2022 at 9:28pmWeb
Show threadTilmann SchoberNov 18, 2022
@gpollara Reminds me of CRISPR which is originally also an antiviral tool of bacteria (and not a biotech thing 😉)