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As someone who regularly uses screen readers and works with blind colleagues who rely on screen readers to access the internet, please let me assure you that using #hashtags within the body of a post is not a problem. You don’t need to move them to the end! It is helpful to use #CamelCase to avoid gibberish for many word combos, but the extra # is so minimal as to disappear given how much else screen readers say & how fast they speak to experienced users.