Thinking about how sign language would work for people who live and work in space, like in Planetes or the Belters in The Expanse. Modern sign language like ASL relies on a lot of emoting and body language, but obviously you don't have that in a space suit, which is a big reason for everyone to know a sign language. So you'd probably wind up with a halfway point between that, and the hand signals that cops and soldiers use.
Signing would be necessary. Electronic comms don't always work. Sometimes you have to communicate visually, especially if there's a lot of different generations of hardware out there. You'd probably have something more focused on exaggerated hand signals and body language, since you probably don't have facial expressions and fine dexterity to rely on, and you'd be doing it at further ranges than conversational sign language as it currently exists.