A supportive commentary on the U.S. EPA's decision to abandon the Integrated Risk Information System (IRIS) and distribute hazard identification and dose-response assessment tasks to individual program offices:
https://www.acsh.org/news/2026/05/19/adios-iris-50131
Although IRIS has become a chokepoint, if not an actual block, on risk assessments, there is no data to show that this change will improve the speed, accuracy, or consistency of risk assessments.

Adios, IRIS
The EPA’s decision to end the use of IRIS for developing chemical risk assessments is a fundamental change in how the agency will decide what chemical hazards mean for regulation. By returning hazard and dose-response assessments to individual program offices, EPA may gain flexibility and scientific currency, but it risks recreating the very inconsistency IRIS was designed to prevent.

