PLOS BiologyBrain #pericytes are critical regulators of endothelial barrier function. @Ahuja_Suchit @SarahChildsYYC &co show that the TF nkx3.1 is critical for generating an intermediate precursor cell state necessary for normal development of pericytes #PLOSBiology https://plos.io/4bedKiE
The development of brain pericytes requires expression of the transcription factor nkx3.1 in intermediate precursors
Brain pericytes are critical regulators of endothelial barrier function. In this study, the authors reveal that expression of the transcription factor nkx3.1 is critical for the generation of an intermediate precursor cell state necessary for the normal development of brain pericytes.