How do integrins and paxillin interact at #FocalAdhesions? This study presents a 3D structure of the LIM3 domain of #paxillin, revealing a direct association between paxillin and the cytoplasmic tail of the #integrin beta subunit #PLOSBiology https://plos.io/3TrtFUw
A flexible loop in the paxillin LIM3 domain mediates its direct binding to integrin β subunits

How do integrins and paxillin interact at focal adhesions? Here, the authors present a 3D-structure of the LIM3 domain of paxillin which reveals a direct association between paxillin and the cytoplasmic tail of the integrin beta subunit.