PLOS BiologyNon-spike protein mutations in #SARSCoV2, likely to impact viral properties, are understudied. This study shows that a #nucleocapsid protein mutation in Delta variant enhances viral growth in vitro & in vivo by increasing viral genome #encapsidation @PLOSBiology https://plos.io/4iBYsaI
Variant mutation G215C in SARS-CoV-2 nucleocapsid enhances viral infection via altered genomic encapsidation
Mutations outside the spike protein in SARS-CoV-2, which are likely to impact viral properties, are currently understudied. This study shows that a nucleocapsid protein mutation in the Delta variant enhances viral growth in vitro and in vivo by increasing viral genome encapsidation.