@trainDS Our (human's) bodies make E from T. To complicate things, high levels of either E or T tend to put the brakes on production of sex hormones: since that starts with T, we stop making our own T.

Body builders have this problem when they over boost their T levels.

However, your body could have other issues that are making this worse. Something that rarely gets checked (even in AMAB) is poor conversion of T to 5DHT. 5DHT is the most effective form of T, and it doesn't convert to E. So if you don't convert it well you have less effects of T, and more E. [And you have less "Male Pattern Baldness".] The medical name for this is 5α-reductase deficiency. Note that for it to have an effect, you don't need complete loss of function.

Another place that can affect this would be loss (or reduced) function in the pathway eliminating E in your liver ... then even if your body makes a normal amount, it could build up. Check on CPY (enzymes) that act on E; it could be some foods or medications you take are inhibiting one of these.

(Maybe I've studied hormones too much ... mark it up to autism)
#hormonePathways #testosterone #estrogen #liverEnzymes #CYP