Pinto et al. present SCINKD as a framework to identify unannotated sex chromosomes and curate diploid genome assemblies from a single individual.

🔗 https://doi.org/10.1093/molbev/msag067

#evobio #molbio #compbio

Sex chromosome identification and genome curation from a single individual with SCINKD

Abstract. In most animal species, the sex-determining pathway is typically initiated by the presence/absence of a primary genetic cue at a critical point d

OUP Academic

Didelot et al. present the R package DiagnoDating for diagnosing issues in a reconstructed dated phylogeny, including outlier detection, posterior predictive checking and residual analysis.

🔗 https://doi.org/10.1093/molbev/msag093

#evobio #molbio #compbio #phylogeny

DiagnoDating: diagnostics for dated phylogenies in microbial population genetics

Abstract. Microbial population genetic studies often involve the use of a dated phylogeny to show how the genomes are related over a relevant timescale. Ma

OUP Academic

Daniel Huson introduces displacement-optimized tanglegrams (DO-tanglegrams), a new approach that applies equally to trees and rooted phylogenetic networks, performing better than cophylo on trees and then NN-tanglegram on networks.

🔗 https://doi.org/10.1093/molbev/msag066

#evobio #molbio #compbio

McArthur et al. present piqtree, an easy to use, open-source Python package that provides Python script-based control of IQ-TREE’s phylogenetic inference engine.

🔗 https://doi.org/10.1093/molbev/msag061

#evobio #molbio #compbio

@sishuowang & Meade introduce phyloHessian to enable the use of complex mixture substitution models in molecular dating. Empirical analysis of ancient symbiont lineages leads to a revised understanding of their host association origins.

🔗 https://doi.org/10.1093/molbev/msag039

#evobio #molbio #compbio

Robbins, Liu & Kelly present RECUR, a method for identifying recurrent amino acid substitutions from multiple sequence alignments that is fast, easy to use, and scalable to thousands of sequences.

🔗 https://doi.org/10.1093/molbev/msag036

#evobio #molbio #compbio

Deng et al. present TreeProfiler, a tool for automated annotation and interactive exploration of hundreds of features along large gene and species trees, with seamless summarization of mapped traits at internal nodes.

🔗 https://doi.org/10.1093/molbev/msag028

#evobio #molbio #compbio

Martí-Gómez et al. developed gpmap-tools, integrating models for inference, phenotypic imputation, and error estimation from multiplex assays of variant effect data or natural sequences in the presence of genetic interactions.

🔗 https://doi.org/10.1093/molbev/msag023

#evobio #molbio #compbio

Anchieri et al. benchmark the inference of selection with aDNA-like time series datasets, showing that ApproxWF can accurately estimate selection with datasets of ∼100 individuals when selection is strong.

🔗 https://doi.org/10.1093/gbe/evaf234

#genome #evolution #compbio

Ramos-González et al. present PharaohFUN, a web application designed for the evolutionary and functional analysis of protein sequences in photosynthetic eukaryotes, leveraging orthology relationships.

🔗 https://doi.org/10.1093/molbev/msag011

#evobio #molbio #compbio