Biostatistics for Biomedical Research has a new section showing how to compute the sample size needed to characterize an entire distribution (e.g., all its quantiles).
http://hbiostat.org/bbr/nonpar.html#sec-nonpar-ecdf #bbrcourse @VUMCbiostat #statistics #biostatisticsBiostatistics for Biomedical Research - 7 Nonparametric Statistical Tests
New blog article in Statistical Thinking: Grant proposal template for developing and validating predictive biostatistical models:
https://fharrell.com/post/modplan #StatThink #rmscourse #bbrcourse @VUMCbiostatStatistical Thinking - Biostatistical Modeling Plan
This is an example statistical plan for project proposals where the goal is to develop a biostatistical model for prediction, and to do external or strong internal validation of the model.
Case study on invalidity of change from baseline in which a strong nonlinear effect of baseline makes average change from baseline uninterpretable:
http://hbiostat.org/bbr/change.html#sec-change-ex #bbrcourse #statistics #biostatistics @VUMCbiostat @EdgeforScholars
Biostatistics for Biomedical Research - 14 Transformations, Measuring Change, and Regression to the Mean
RT @[email protected]
#Statistics question of the day: Why criticize a Bayesian's choice of prior and never question your own choice of the ratio of type II assertion probability to type I assertion probability Ξ²/Ξ± being set to 4.0? (Ξ±=0.05, Ξ²=0.2) #Bayes #bbrcourse @[email protected]
π¦π: https://twitter.com/f2harrell/status/1285900436533317634

Frank Harrell on Twitter
β#Statistics question of the day: Why criticize a Bayesian's choice of prior and never question your own choice of the ratio of type II assertion probability to type I assertion probability Ξ²/Ξ± being set to 4.0? (Ξ±=0.05, Ξ²=0.2) #Bayes #bbrcourse @vandy_biostatβ
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