Stephen Matheson🌵🌲Rps27 and Rps27l proteins are functionally interchangeable...
have been evolutionarily retained because the divergence of their expression patterns has resulted in both genes becoming necessary for achieving adequate total expression of the RP across cell types.
#MolecularEvolution
#Subfunctionalization
#geneduplication
#evolution
Subfunctionalized expression drives evolutionary retention of ribosomal protein paralogs Rps27 and Rps27l in vertebrates
Ribosomal proteins Rps27 (eS27) and Rps27l (eS27L) are an ancient pair of duplicated genes that encode functionally interchangeable proteins, yet have been evolutionarily retained because both copies are necessary to achieve protein expression across cell types.