A
#zebrafish model of
#scoliosis due to abnormal
#ciliary beating & ependymal polarity defects reveals that uneven distribution of
#Urotensin is a major cause of
#SpinalCurvature; abnormal Urotensin signaling is also seen in human patients
#PLOSBiology https://plos.io/3JbuKuX
Ependymal polarity defects coupled with disorganized ciliary beating drive abnormal cerebrospinal fluid flow and spine curvature in zebrafish
Idiopathic scoliosis is the most common spinal deformity diagnosed in childhood or early adolescence. A zebrafish model of scoliosis due to abnormal ciliary beating and ependymal polarity defects reveals that uneven distribution of Urotensin neuropeptides is a major cause of spinal curvature; abnormal Urotensin signaling is also observed in human idiopathic scoliosis patients.
A
#zebrafish model of
#scoliosis due to abnormal
#ciliary beating & ependymal polarity defects reveals that uneven distribution of
#Urotensin is a major cause of
#SpinalCurvature; abnormal Urotensin signaling is also seen in human patients
#PLOSBiology https://plos.io/3JbuKuXEpendymal polarity defects coupled with disorganized ciliary beating drive abnormal cerebrospinal fluid flow and spine curvature in zebrafish
Idiopathic scoliosis is the most common spinal deformity diagnosed in childhood or early adolescence. A zebrafish model of scoliosis due to abnormal ciliary beating and ependymal polarity defects reveals that uneven distribution of Urotensin neuropeptides is a major cause of spinal curvature; abnormal Urotensin signaling is also observed in human idiopathic scoliosis patients.
A
#zebrafish model of
#scoliosis due to abnormal
#ciliary beating & ependymal polarity defects reveals that uneven distribution of
#Urotensin is a major cause of
#SpinalCurvature; abnormal Urotensin signaling is also seen in human patients
#PLOSBiology https://plos.io/3JbuKuXEpendymal polarity defects coupled with disorganized ciliary beating drive abnormal cerebrospinal fluid flow and spine curvature in zebrafish
Idiopathic scoliosis is the most common spinal deformity diagnosed in childhood or early adolescence. A zebrafish model of scoliosis due to abnormal ciliary beating and ependymal polarity defects reveals that uneven distribution of Urotensin neuropeptides is a major cause of spinal curvature; abnormal Urotensin signaling is also observed in human idiopathic scoliosis patients.
PLOS Biology
