Crystals of His15 acetamide-modified lysozyme had similar unit-cell parameters to the unmodified tetragonal form but refinement was only possible in an orthorhombic system #AcylatedLysozyme #Crystallization #SpaceGroupAnalysis https://doi.org/10.1107/S2053230X2500010X
The structure of His15 acetamide-modified hen egg-white lysozyme: a nice surprise from an old friend

Chemical modification of lysozyme at His15 using iodoacetamide was investigated structurally. Crystallization of the chemically modified enzyme using a protocol which yields tetragonal crystals gave orthorhombic crystals with similar unit-cell parameters.

Acta Crystallographica Section F