Albert CardonaApr 17

For anyone still submitting biology papers with p-values:

"Estimation statistics should replace significance testing", Claridge-Chang and Assam, 2016
https://www.nature.com/articles/nmeth.3729 (and also at https://zenodo.org/records/60156 ).

#statistics #SignificanceTesting #pvalue #ScientificPublishing

Estimation statistics should replace significance testing - Nature Methods

Nature
Bjørn SætrevikMar 25

Imagine you preregistered study with tests A and B for a directed hypothesis H, but did not specify one-tailed or two-tailed testing. Test A is in the predicted direction, but p = between .05 and .09. Test B is in the non-predicted direction, but p < .05. How do you report results?

#PreRegistration #OpenScience #NHST #SignificanceTesting #pValue

One-tailed, test A supports H, but test B does not
0%
Two-tailed, B supports non-direct. H, while A not
0%
Two-tailed, B treated as counter to directional H
50%
Other? Please specify in comment
50%
Poll ended at .
katch wreckSep 22, 2023

`Intuitively, if the restricted #estimator is near the maximum of the #likelihood function, the score should not differ from zero by more than sampling error. While the finite sample #distributions of score tests are generally unknown, they have an #asymptotic χ2-distribution under the null #hypothesis as first proved by C. R. Rao in 1948, a fact that can be used to determine statistical #significance.`

https://en.wikipedia.org/wiki/Score_test

#statistics #stats #significanceTest #significanceTesting

Score test - Wikipedia