Amelia Cervera 🧬Apr 9, 2025

Turnover of retroelements and satellite DNA drives centromere reorganization over short evolutionary timescales in Drosophila.

#Transposons #Retrotransposons #SatelliteDNA #Centromeres #Drosphila

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002911

Turnover of retroelements and satellite DNA drives centromere reorganization over short evolutionary timescales in Drosophila

Centromeres reside in rapidly evolving, repeat-rich genomic regions, despite their essential function in chromosome segregation. This study of centromere evolution over short evolutionary timescales in Drosophila reveals dramatic centromere reorganization involving recurrent shifts between retroelements and satellite DNAs.

Amelia Cervera 🧬Jan 16, 2025
Multi-tissue characterization of the constitutive heterochromatin proteome in Drosophila identifies a link between satellite DNA organization and transposon repression.
#SatelliteDNA #Centromers #Chromocenters #piRNA #Transposons #TEs #Drosophila
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002984
Multi-tissue characterization of the constitutive heterochromatin proteome in Drosophila identifies a link between satellite DNA organization and transposon repression

Pericentromeric heterochromatin clusters into nuclear foci known as chromocenters, the proteome of which remains largely unknown. This study uses quantitative mass spectrometry to characterize the chromocenter-associated proteome in multiple tissues, identifying a link between satellite DNA-binding proteins and transposon repression during embryogenesis.