The EMBO JournalWhat is the significance of interaction between #immune #checkpoint ligands #CD80 and #PD1L?
David Sansom and coworkers at UCL Institute of Immunity and Transplantation show that selective CD80 #transendocytosis via its cognate receptor #CTLA4 is needed to liberate PD-1L for PD-1 binding and immune response suppression
https://www.embopress.org/doi/10.15252/embj.2022111556
David Sansom and coworkers at UCL Institute of Immunity and Transplantation show that selective CD80 #transendocytosis via its cognate receptor #CTLA4 is needed to liberate PD-1L for PD-1 binding and immune response suppression
https://www.embopress.org/doi/10.15252/embj.2022111556