Stefan Johansson, MD PhDOct 24, 2023

Tuesday morning thoughts…
The #NeoCLEAR study including ~1100 infants did (IMHO) show that lumbar punction in infants born at 27-44 weeks, were done better in the sitting position (higher success rate).πŸ‘
On the other side, this new #Cochrane meta-analysis on this topic, adding data from 4 small & less well-designed studies, shares confusing conclusion… πŸ€·β€β™‚οΈ

How to overcome this gap between good RCTs and clinical #NeoEBM practice?!

https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD015592.pub2/full

https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(22)00343-1/fulltext

#NeoMastodon

Stefan Johansson, MD PhDDec 10, 2022

Interesting #NeoEBM paper about meningitis and outcomes in #ELBW infants.
I think the most interesting part is that less LPs are done over time, and therefore fewer diagnosed.
Let us all read and learn from the #NeoCLEAR study too!

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2799308

https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(22)00343-1/fulltext

Incidence of and Outcomes After Late-Onset Meningitis Among Children Born Extremely Preterm

This cohort study reports the incidence of late-onset meningitis during birth hospitalization of neonates born extremely preterm and the neurodevelopmental outcomes at 18 to 26 months’ corrected age.