Researchers at The University of Texas MD Anderson
#Cancer Center have discovered that lactate-producing
#intratumoral #bacteria drives resistance to
#radiation therapy
#Medical #sflorghttps://www.sflorg.com/2023/10/med10192301.html
Lactate-producing bacteria inside tumors promote resistance to radiation therapy
Targeting intratumoral bacteria could potentially overcome treatment resistance
#Intratumoral delivery of an
#engineered #oncolytic #virus (DNX-2401) targeting
#glioblastoma (#GBM ) cells combined with subsequent
#immunotherapy was safe and improved survival outcomes in a subset of patients with recurrent GBM
#Cancer #Medical #Neuroscience #sflorghttps://www.sflorg.com/2023/05/med05152301.html 
Combined delivery of engineered virus with immunotherapy is safe and improves outcomes in subset of patients with glioblastoma
Study validates safety of combination approach, offering possibilities to adapt treatment strategies to optimize outcomes
Scientific Frontline