StructBiolCommunicationsSep 11, 2025
Crystal structures of a clinically used histone deacetylase inhibitor, vorinostat, bound to the previously unidentified off-target proteins carbonic anhydrases II and IX are reported #HDACInhibitors #SAHA #Vorinostat https://doi.org/10.1107/S2053230X25007447
GeekooJun 12, 2025

A newly discovered gene may explain why some prostate cancers become deadly — and how we might stop them. #ProstateCancer #GeneTherapy #HDACinhibitors

https://geekoo.news/the-hidden-gene-driving-prostate-cancers-dark-turn/

The Hidden Gene Driving Prostate Cancer’s Dark Turn | Geekoo

A single gene may hold the key to why prostate tumors turn aggressive — and scientists now have a way to switch it off using approved drugs.

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