#Gasdermins (GSDMs) are pore-forming proteins involved in #CellDeath & #inflammation. @jianbin_ruan explores a #PLOSBiology study of the evolution of GSDMs in metazoa, highlighting the role of GSDME in #pyroptosis. Primer: https://plos.io/3nyd4By Paper: https://plos.io/3p6klcm
An ancient defense mechanism: Conservation of gasdermin-mediated pyroptosis

Gasdermin (GSDM) is a family of pore-forming proteins involved in various cellular processes such as cell death and inflammation. This Primer explores a PLOS Biology study of the evolutionary history of GSDMs across metazoan species, including Amphioxus, highlighting the conservation and divergence of GSDME in inducing pyroptosis in response to infection.

#Gasdermins (GSDMs) are pore-forming proteins involved in #CellDeath & #inflammation. @jianbin_ruan explores a #PLOSBiology study of the evolution of GSDMs in metazoa, highlighting the role of GSDME in #pyroptosis. Primer: https://plos.io/3nyd4By Paper: https://plos.io/3p6klcm
An ancient defense mechanism: Conservation of gasdermin-mediated pyroptosis

Gasdermin (GSDM) is a family of pore-forming proteins involved in various cellular processes such as cell death and inflammation. This Primer explores a PLOS Biology study of the evolutionary history of GSDMs across metazoan species, including Amphioxus, highlighting the conservation and divergence of GSDME in inducing pyroptosis in response to infection.

#Gasdermins (GSDMs) are pore-forming proteins involved in #CellDeath & #inflammation. @jianbin_ruan explores a #PLOSBiology study of the evolution of GSDMs in metazoa, highlighting the role of GSDME in #pyroptosis. Primer: https://plos.io/3nyd4By Paper: https://plos.io/3p6klcm
An ancient defense mechanism: Conservation of gasdermin-mediated pyroptosis

Gasdermin (GSDM) is a family of pore-forming proteins involved in various cellular processes such as cell death and inflammation. This Primer explores a PLOS Biology study of the evolutionary history of GSDMs across metazoan species, including Amphioxus, highlighting the conservation and divergence of GSDME in inducing pyroptosis in response to infection.