In Florida people should “always assume” there’s a risk for Naegleria fowleri infection... When water containing the amoeba enters the nose, the organism can travel to the brain and cause an almost-always fatal brain infection called primary amebic meningoencephalitis.

https://www.healthline.com/health-news/person-dies-from-brain-eating-amoeba-after-sinus-rinse

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Person Dies From Brain-Eating Amoeba After Sinus Rinse

A person in southwest Florida died after being infected with Naegleria fowleri, commonly known as the “brain-eating amoeba.”

Healthline Media