The combination of dasatinib (a leukemia treatment) and quercertin (a common polyphenol found in vegetables) remove senescent cells and is being studied as an anti-aging treatment. A new mouse study finds that the combination reduces the myelin sheath around nerve cells, causing neuropathology in the brain.

Summary: https://www.sciencealert.com/promising-anti-aging-drug-may-cause-brain-damage-scientists-warn

Original paper (not open access): https://www.pnas.org/doi/10.1073/pnas.2524897123

#Science #Aging #Dasatanib #Quercertin #Demyelination #BrainDamage