The structure of a complex between human RAGE ectodomain and S100A6 variant Y84C provides a possible model for S100 covalent homodimerization that is fully compatible with RAGE binding #S100Proteins #Cysteines #CovalentHomodimerization https://doi.org/10.1107/S2053230X26002992

Last year ended up with some lab related good news. Our hyp. paper on #protein #disulfide isomerases (PDIs) got accepted on #redoxbiology. We provide hints for additional non-catalytic #cysteines in PDIs that may contribute to their function/structure. https://doi.org/10.1016/j.redox.2022.102583 1/2