How do long-lived neurons, which lack the mechanisms that keep other cells from accumulating DNA damage, maintain their genomic and functional integrity over a lifetime? Read more about how Berkeley Lab #BioMBIB scientists and their Harvard T.H. Chan School of Public Health colleagues found out -->

https://newscenter.lbl.gov/2025/01/13/unraveling-the-mysteries-of-dna-damage-in-the-brain/

hashtag#Aging hashtag#NeurodegenerativeDisease

Unraveling the Mysteries of DNA Damage in the Brain

Berkeley Lab News Center

#BioMBIB's Eva Nogales is an international leader in the use of cryo-electron microscopy. In December, she was recognized with two separate awards in her native Spain:

- The Extraordinary Medal for Scientific Merit from the Spanish High Council for Scientific Research

- And an honorary doctorate from Carlos III University in Madrid

Congratulations Eva!

@berkeleylab
https://biosciences.lbl.gov/2025/01/08/nogales-garners-two-international-accolades/

Nogales Garners Two International Accolades - Biosciences Area

Eva Nogales, a senior faculty scientist Molecular Biophysics and Integrated Bioimaging (MBIB) Division, was honored in her native Spain for her work in the field of visualization of macromolecular function.

Biosciences Area

Biochemist and Nobel Laureate Jennifer Doudna, a faculty scientist in #BioMBIB at @berkeleylab has received the National Medal of Technology and Innovation, the nation’s highest honor for technological achievement for her work developing the #CRISPR-Cas9 gene-editing technology. This method is the basis of many promising technologies, including tools to diagnose and treat disease, and has many applications for the development of improved crops, biofuels, and bioproducts.

https://biosciences.lbl.gov/2025/01/07/doudna-awarded-national-medal-technology-innovation/

Biosciences' Doudna Awarded National Medal of Technology and Innovation - Biosciences Area

Biochemist Jennifer Doudna, a faculty scientist in the Molecular Biophysics and Integrated Bioimaging (MBIB) Division, has received the National Medal of Technology and Innovation, the nation’s highest honor for technological achievement.

Biosciences Area
Science Magazine has named #BioMBIB research as a runner-up for 2024 Breakthrough of the Year! Faculty Scientist Carolyn Larabell and Valentina Loconte performed soft X-ray tomography (SXT) at the Advanced Light Source on cells of the host organism, Braarudosphaera bigelowii, a marine algae. The breakthrough paper describes the first known nitrogen-fixing organelle within a eukaryotic cell. @berkeleylab

https://www.science.org/content/article/breakthrough-2024#section_breakthrough

#BioMBIB researchers collected X-ray diffraction data at the Advanced Light Source on a Baylor College of Medicine project that may lead to a reversible contraception method for men

https://biosciences.lbl.gov/2024/09/04/a-promising-compound-for-reversible-male-contraception/

@berkeleylab

A Promising Compound for Reversible Male Contraception - Biosciences Area

Researchers identified a small-molecule protein inhibitor—analyzed using protein crystallography at the ALS—that reversibly suppresses male fertility in mice.

Biosciences Area

Looking for a postdoc position?

We have three openings on #TeamBioSci at Berkeley Lab:

Mass Spectrometry Postdoctoral Fellow - Ambient Infrared Laser Ablation in #BioMBIB - Position # 102799

Computational Postdoctoral Fellow - Optimization and Learning for Cryo-Electron Microscopy in #BioMBIB - Position # 102780

Biologist Postdoctoral Fellow in #BioBSE in the Joint BioEnergy Institute’s Deconstruction Division - Position # 102552

Learn more and apply here:

https://jobs.lbl.gov/et/rWgbpVSH/page/biosciences-1653

#BioMBIB researchers are developing and applying techniques to determine where chemical reactions take place in active sites of a copper-liquid interface at relevant time scales. The work can enable new insights related to the catalytic mechanism and durability issues in artificial photosynthesis systems for future solar fuels.
@berkeleylab
https://biosciences.lbl.gov/2024/08/30/paving-the-way-for-a-solar-fuels-future/
Paving the Way for a Solar Fuels Future - Biosciences Area

A roundup of “Five Ways LiSA is Advancing Solar Fuels,” included a project led by MBIB Division Director Junko Yano that could enable characterization, under real-world conditions, of the chemical reactions that take place where a metal catalyst and electrolyte meet.

Biosciences Area

#BioMBIB's Setsuko Wakao works with an interdisciplinary team to deliver a deeper understanding of a group of algae, called diatoms, and their potential applications. Not only are diatoms important in carbon cycling, they may be able to be used to make plastics or silicon, and could play a role in recycling rare metals. @berkeleylab

https://buff.ly/3MlIVhK

Research on Diatoms Explores New Paths to Support Sustainability

Attention Job Seekers: We have several open positions on #TeamBioSci at @berkeleylab

Filamentous Fungi Research Scientist in #BioEGSB - Position # 102409

Laboratory Ecosystem Research Scientist in #BioEGSB - Position # 102408

Postdoctoral Fellow (Health Sciences) in #BioBSE - Position # 101639

Biologist Postdoctoral Fellow in #BioMBIB - Position # 102365

Computational Postdoctoral Fellow (Optimization and Learning for Imaging) in #BioMBIB - Position # 101196

https://jobs.lbl.gov/et/rWgbpVSH/page/biosciences-1653

A team of scientists, including #BioMBIB's Eva Nogales, used high-resolution cryo-electron microscopy to look at a protein complex that grants access to our DNA. This data could help develop better therapies for cancer and Alzheimer's.

@berkeleylab
https://biosciences.lbl.gov/2024/08/07/a-better-understanding-of-dna-unpacking/

A Better Understanding of DNA Unpacking - Biosciences Area

Using specialized equipment, including cryo-EM researchers were able to study the atomic structure of a complex that allows enzymes to access DNA.

Biosciences Area