Actl7b deficiency leads to mislocalization of LC8 type dynein light chains and disruption of murine spermatogenesis https://doi.org/10.1242/dev.201593
Cylicins are a structural component of the sperm calyx being indispensable for male fertility in mice and human https://elifesciences.org/articles/86100
this last one having multiple Andronet members in the author list.
#Andrology #ReproductiveBiology #Reproduction
Actl7b deficiency leads to mislocalization of LC8 type dynein light chains and disruption of murine spermatogenesis
Summary: Actl7b-deficient mice display spermatogenic arrest, which is likely due to loss of the interaction of ACTL7B with DYNLL1/DYNLL2, a spermatid cytoskeleton protein.