Bisphenol A (BPA), a ubiquitous chemical in plastics, impairs male reproductive function through oxidative stress, but paraprobiotics like heat-treated Enterococcus faecalis (FK-23) can successfully counteract this damage and restore sperm motility.
#ReproductiveBiology #Toxicology #Microbiology #Medicine #sflorghttps://www.sflorg.com/2026/05/bio05152601.html
Paraprobiotic counteracts damage to male fertility from BPA in plastic
Learn how the paraprobiotic FK-23 protects male fertility by neutralizing oxidative stress caused by BPA plastic exposure via the gut-immune axis.
The navigational abilities of human and mammalian sperm, along with early embryonic development, are significantly impaired by the lack of gravity in extraterrestrial environments.
#Astrobiology #SpaceMedicine #ReproductiveBiology #Biology #sflorghttps://www.sflorg.com/2026/03/bio03272601.html
Human sperm may get lost in space
Having a baby in space may require a bit more direction
Fecal transplants from older,
#estropausal female mice significantly improve
#ovarian function, reduce tissue inflammation, and enhance overall fertility in younger female mice.
#Gerontology #ReproductiveBiology #Microbiology #sflorg https://www.sflorg.com/2026/03/bio03032601.html
Fecal Transplants from Older Mice Significantly Improve Ovarian Function and Fertility in Younger Mice
The surprising findings shed light on the little-known relationship between the microbiome and the reproductive system.
A single
#maternal exposure to a
#toxic #fungicide during
#pregnancy increases the risk of disease and
#inherited health problems across 20 subsequent
#generations through stable alterations in reproductive cells.
#Epigenetics #Toxicology #ReproductiveBiology #sflorghttps://www.sflorg.com/2026/02/epi02202601.html
Toxic exposure creates disease risk over 20 generations
The research has implications for deciphering rising disease rates among humans
'The effect of antioxidants on the morphology and function of ovaries in rats inflammatory process (pregnancy) within the framework of the analysis of the assessment of their action and effectiveness on nuclear and cytoplasmic maturation of oocytes' - a Bulletin Of Medical And Biological Research article on #ScienceOpen:
📌 https://www.scienceopen.com/document?vid=14cb6417-373a-429f-8dca-79c2d55e6984
#ReproductiveBiology #AntioxidantResearch #PregnancyInflammation #OxidativeStress #OvarianHealth
The effect of antioxidants on the morphology and function of ovaries in rats inflammatory process (pregnancy) within the framework of the analysis of the assessment of their action and effectiveness on nuclear and cytoplasmic maturation of oocytes
<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d3987520e61">The study aimed to investigate the effect of various antioxidants on the morphological
and functional characteristics of ovaries in pregnant Wistar rats under conditions
of systemic inflammation. The experimental research was conducted on a total of 20
sexually mature female rats of the Wistar strain, which were divided into five subgroups
with four animals in each. The rats were categorised into the following groups: a
control group (no treatment), an inflammation-induced group (lipopolysaccharide treatment),
and three antioxidant-treated groups, where systemic inflammation was induced and
the females were treated with resveratrol, quercetin, or lycopene. Systemic inflammation
was induced using lipopolysaccharide, and different antioxidants were administered
to the treated subgroups over a specified period from May to June 2023. The research
focused on examining the impact of these antioxidants on oocyte morphology, mitochondrial
function, and the levels of reactive oxygen species and glutathione. Results indicated
that antioxidant treatment significantly improved oocyte morphology by reducing abnormalities
and restoring normal mitochondrial distribution. Rats in the antioxidant-treated group
exhibited reduced levels of reactive oxygen species and elevated concentrations of
glutathione, signalling a reduction in oxidative stress. Additionally, an increase
in the expression of genes associated with antioxidant defence was observed, suggesting
an enhanced antioxidant response. These findings imply that antioxidants can improve
oocyte quality in cases of inflammation-induced oxidative stress, offering new insights
for reproductive biology. The practical relevance of this work lies in its potential
application in reproductive medicine, particularly for patients with inflammation-related
infertility, where antioxidant therapies could contribute to improving oocyte quality
and reproductive outcomes
</p>
🧵 1/ Female #ReproductiveBiology is, unfortunately, notoriously understudied.
So maybe it’s no surprise that a supposedly useless ‘developmental leftover’ in the ovaries could turn out to be...not so useless after all.
Meet the rete ovarii 👇
https://elifesciences.org/articles/106648?utm_source=mastodon&utm_medium=social&utm_campaign=organic_insights
Ovarian Biology: Revisiting the rete ovarii
Long thought to have little relevance to ovarian physiology, the rete ovarii may have a role in follicular dynamics and reproductive health.
🌱Welcome to our Plant Reproduction Week! 🌸
🌎During the next few days, @AnnBot will be highlighting articles from the Special Issue "Plant Reproduction in a Changing Global Environment"
💡Stay tuned!
#PlantReproductionWeek #Botany #PlantScience #ClimateChange #ReproductiveBiology
Researchers have identified an ancient molecular key crucial for sperm to unlock and fertilize an egg, offering new insights into reproduction. This discovery could lead to breakthroughs in fertility treatments and contraceptive development. Understanding these fundamental processes reminds us of the shared biological legacy across species.
#ReproductiveBiology #Science #Innovationhttps://www.nytimes.com/2024/10/17/science/sperm-egg-proteins-key.html
Sperm Can’t Unlock an Egg Without This Ancient Molecular Key
Using Google’s AlphaFold, researchers identified the bundle of three sperm proteins that seem to make sexual reproduction possible.
Challenging the Legacies of Eugenics in Science, Medicine, and Technology
CGS is excited to announce the launch of a new anti-eugenics initiative that
Congratulations to
#Andronet member Hubert Schorle for his two recent publications:
Actl7b deficiency leads to mislocalization of LC8 type dynein light chains and disruption of murine spermatogenesis
https://doi.org/10.1242/dev.201593Cylicins are a structural component of the sperm calyx being indispensable for male fertility in mice and human
https://elifesciences.org/articles/86100this last one having multiple Andronet members in the author list.
#Andrology #ReproductiveBiology #Reproduction
Actl7b deficiency leads to mislocalization of LC8 type dynein light chains and disruption of murine spermatogenesis
Summary: Actl7b-deficient mice display spermatogenic arrest, which is likely due to loss of the interaction of ACTL7B with DYNLL1/DYNLL2, a spermatid cytoskeleton protein.
Scientific Frontline
ScienceOpen
eLife
Annals of Botany
Hari Tulsidas
Anne Fausto Sterling
Andronet COST Action 20119