@stuartcantrill what is going on here? Alcohol free gin… distillate etc.
Andrei Yudin
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Prof at the University of Toronto. I look at organic chemistry as a string of combinations of half-reactions.
Direct formation and site-selective elaboration of methionine sulfoximine in polypeptides by Zachary Ball and colleagues at Rice University #ChemicalScience
https://pubs.rsc.org/en/content/articlelanding/2022/SC/D2SC04220G
Direct formation and site-selective elaboration of methionine sulfoximine in polypeptides
Sulfoximines are emerging moieties for medicinal and biological chemistry, due in part to their efficacy in selective inhibition of amide-forming enzymes such as γ-glutamylcysteine synthetase. While small-molecule sulfoximines such as methionine sulfoximine (MSO) and its derivatives are well studied, structures wit
Protobranching is the concept whose fate I follow. As in below, where propane is stabilized by attractive interactions that aren't (clearly) present in either methane or ethane. Paul Schleyer was at the origin of this thing and protobranching has been somewhat controversial. But I just love the whole "destabilization-induced attraction" angle. It takes us back to dialectics and the unity of opposites...
My first post here shows the summary of the talk I have been giving during my sabbatical in Germany (this is typically the first slide I show). It is about how energetically entangled high energy states in organic chemistry are (from conformations to intermediates and transition states in reactions). I have tried to play on the theme of half-reactions using a cultural reference some of you might recognize if you watched Ozark.