What is it about Python that makes developers love fragmentation so much? Sending HTTP requests is a basic capability in the modern world, the standard library should include a friendly, fully-featured, battle-tested, async-ready client. But not in Python, stdlib only has the ugly urllib.request, and everyone is using third party stuff like requests or httpx, which aren't always well maintained. (See also: packaging)
This appears to be a MJML wrapper with a Markdown→HTML converter attached to it. I think generating HTML from code is easier than generating Markdown, since there are many templating tools that understand HTML escaping. And writing HTML is not that hard, especially for your typical emails, so I'm not really sure if this library would be helpful in the long run.