Mastodawn

Magnetic resonance microscopy maps widespread effects of Alzheimer’s disease on brain structures and behavior in mice:

https://www.nature.com/articles/s41593-025-02199-4

Magnetic resonance microscopy maps widespread effects of Alzheimer’s disease on brain structures and behavior in mice - Nature Neuroscience

Alzheimer’s disease alters brain structure broadly, but its regional impact is poorly mapped. Here, the authors show that App and Psen1 mutations in mice cause volume changes across 231 regions, which are associated with individual differences in behavior.

Nature

genenetwork Dec 26

Rat Genome Database Dec 22

Complex Trait Community / Rat Genomics (CTC-RG), please vote for 2026 meeting time/location.
Tentative options:
• Portland, Maine with Vivek Kumar/JAX – Oct
• Houston, Texas with Peter Doris – Oct-Nov
• San Diego, CA with Abe Palmer – June or Sept
https://docs.google.com/forms/d/e/1FAIpQLScvHgnWb9QXfoko7A7OAZzKxbmXMOsZIWp2vjKp70qCpXIgzg/viewform

CTC 2026 Organizational Survey

This is a survey to pick the location of the 2026 meeting of the Complex Trait Consortium / Rat Genome (CTC / CTC-RG). More details about the this conference series on its home page: http://www.complextrait.org/

Google Docs

genenetwork Dec 19

PANGENOMICS | 07-13 June 2026
Hands-on pangenome graphs, HPRC methods & tools (PGGB, ODGI, PanGenie). Apply by 03 February:
https://meetings.embo.org/event/26-pangenomics

genenetwork Dec 13

Ludovic Courtès Dec 12

“With or without Guix: Deploying complex software stacks on major supercomputers” 👇
https://hpc.guix.info/blog/2025/12/with-or-without-guix-deploying-complex-software-stacks/

A Guix-based workflow that goes from continuous integration to supercomputers with ‘guix pack’.

#Guix #HPC #EuroHPC

With or without Guix: Deploying complex software stacks on major supercomputers

genenetwork Nov 11

Ross Mounce Nov 10

Oxford and Harvard libraries now publishing their own diamond open access journals. Love it. ❤️

Paying hundreds of millions to big commercial publishers isn't the only way of supporting researchers to publish their research.

Oxford: https://www.bodleian.ox.ac.uk/shox#collapse5381526

Harvard: https://library.harvard.edu/about/news/2024-04-23/harvard-library-launching-harvard-open-journals-program

#DiamondOA #OpenAccess

SHOx: Shortform Hosting at Oxford

genenetwork Nov 9

BioHackrXiv Nov 6

"AI in Practice: Insights from a Community Survey of Biohackathon Participants" https://doi.org/10.37044/osf.io/pza7v_v1

"Findings reveal that most participants are frequent AI users, with tools like ChatGPT, Gemini, and Claude widely adopted, with ChatGPT as number one response. AI is primarily used to assist or draft tasks in coding, research, and writing, while full task automation remains uncommon, reflecting a preference for AI as a collaborative aid rather than a replacement." https://index.biohackrxiv.org//2025/10/12/pza7v.html

#biohackathon #AI #BH25JP

OSF

genenetwork Nov 4

BioHackrXiv Nov 4

our preview website has been revamped: https://preview.biohackrxiv.org/

#biohackrxiv #preprint #biohackathon

genenetwork Oct 22

Complex Traits Consortium meeting in Barcelona is on! Many interesting people and talks: https://complextrait.org/meetings/ctc2025/program.html

Program CTC-RG2025

genenetwork Oct 8

HPRC Biohackathon Memphis TN with Erik Garrison, Andrea Guarracino, Richard Durbin, Adam Novak, Pjotr Prins, Enza Colonna and others!

genenetwork Oct 6

Human Pangenome Reference Consortium annual meeting organized by Washington University St. Louis and University of Tennessee Health Science Center at the historic Memphis Central Railway Station Hotel! https://humanpangenome.org/