An allosteric cyclin E-CDK2 site mapped by paralog hopping with covalent probes https://covalentmodifiers.blogspot.com/2024/09/an-allosteric-cyclin-e-cdk2-site-mapped.html?utm_source=dlvr.it&utm_medium=mastodon

Nuclear Receptors: A new mode of inhibition https://covalentmodifiers.blogspot.com/2024/09/nuclear-receptors-new-mode-of-inhibition.html?utm_source=dlvr.it&utm_medium=mastodon

Selective Covalent Inhibiting JNK3 by Small Molecules for Parkinson's Diseases https://covalentmodifiers.blogspot.com/2024/09/selective-covalent-inhibiting-jnk3-by.html?utm_source=dlvr.it&utm_medium=mastodon

Development of ketalized unsaturated saccharides as multifunctional cysteine-targeting covalent warheads https://covalentmodifiers.blogspot.com/2024/09/development-of-ketalized-unsaturated.html?utm_source=dlvr.it&utm_medium=mastodon

From Mechanism-Based Retaining Glycosidase Inhibitors to Activity-Based Glycosidase Profiling https://covalentmodifiers.blogspot.com/2024/09/from-mechanism-based-retaining.html?utm_source=dlvr.it&utm_medium=mastodon

SuFEx Chemistry Enables Covalent Assembly of a 280-kDa 18-Subunit Pore-Forming Complex https://covalentmodifiers.blogspot.com/2024/09/sufex-chemistry-enables-covalent.html?utm_source=dlvr.it&utm_medium=mastodon

Targeted Protein Localization by Covalent 14–3–3 Recruitment https://covalentmodifiers.blogspot.com/2024/08/targeted-protein-localization-by.html?utm_source=dlvr.it&utm_medium=mastodon

Aminomethyl Salicylaldehydes Lock onto a Surface Lysine by Forming an Extended Intramolecular Hydrogen Bond Network https://covalentmodifiers.blogspot.com/2024/08/aminomethyl-salicylaldehydes-lock-onto.html?utm_source=dlvr.it&utm_medium=mastodon

Discovery of a Covalent Inhibitor of Pro-Caspase-1 Zymogen Blocking NLRP3 Inflammasome Activation and Pyroptosis https://covalentmodifiers.blogspot.com/2024/08/discovery-of-covalent-inhibitor-of-pro.html?utm_source=dlvr.it&utm_medium=mastodon

Discovering Covalent Cyclic Peptide Inhibitors of 2 Peptidyl Arginine Deiminase 4 (PADI4) Using mRNA3 Display with a Genetically Encoded Electrophilic 4 Warhead https://covalentmodifiers.blogspot.com/2024/08/discovering-covalent-cyclic-peptide.html?utm_source=dlvr.it&utm_medium=mastodon