bioRxiv Synthetic Biology

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PhAGE Enables One-Step Genome Integration of Large DNA Fragments in Escherichia coli https://www.biorxiv.org/content/10.64898/2026.04.23.720475v1?med=mas
A liquid handling platform for standardised quantification of cell-free enzymatic activity encoded by antimicrobial resistance genes https://www.biorxiv.org/content/10.64898/2026.04.23.720151v1?med=mas
yakRNA Design: A semantic multimodal RNA composer https://www.biorxiv.org/content/10.64898/2026.04.22.720245v1?med=mas
Unsupervised protein language models learn patterns of enzyme function https://www.biorxiv.org/content/10.64898/2026.04.23.720319v1?med=mas
A Proteome-Calibrated Mechanistic Digital Twin of the Glioblastoma Astrocyte Derived from Patient Multi-Omic Data https://www.biorxiv.org/content/10.64898/2026.04.23.719998v1?med=mas
Delineating the Transcriptional and Phenotypic Impact from Biotherapeutic Glycoengineering https://www.biorxiv.org/content/10.64898/2026.04.21.719832v1?med=mas
Rational engineering enhances the signal and modularity of an RNA barcoding technology to track gene transfer in microbiomes https://www.biorxiv.org/content/10.64898/2026.04.20.719664v1?med=mas
A novel polymerase III promoter for gene editing in the agricultural pest Ceratitis capitata https://www.biorxiv.org/content/10.64898/2026.04.21.719894v1?med=mas
Selective Hydrolytic Defluorination of Branched Perfluorooctanoic Acid Isomers by a Haloacid Dehalogenase https://www.biorxiv.org/content/10.64898/2026.04.19.719434v1?med=mas
A trainable language model for modulating translation rates in non-model organisms by generating upstream untranslated region sequence libraries https://www.biorxiv.org/content/10.64898/2026.04.18.719341v1?med=mas