Abish Stephen

103 Followers
162 Following
282 Posts

Microbiologist.

Fan of guitars, motorsport and cricket. #biker

Lecturer at Queen Mary University of London.

Work Profilehttps://www.qmul.ac.uk/dentistry/people/profiles/drabishstephen-.html
We did see 'health'-associated taxa increase in abundance post-therapy. There seemed to be a persistent difference in diversity between control group and PID group. We also observed interesting correlations with blood absolute #neutrophil counts and certain oral bacteria. This is certainly worth exploring further as these bacteria are part of the 'hedgehog' consortia in the dental plaque - dynamics are relevant for oral health in general. /end

Happy to see this out! We analysed the dental #microbiome of children with #primaryimmune deficiencies underwent non-surgical therapy. Prevalence of gum disease was higher in this group and the aim was to look at longitudinal data to see if therapy modulated the microbiome. 1/

https://onlinelibrary.wiley.com/doi/10.1111/jcpe.14201

We did see 'health'-associated taxa increase in abundance post-therapy. There seemed to be a persistent difference in diversity between control group and PID group. We also observed interesting correlations with blood absolute #neutrophil counts and certain oral bacteria. This is certainly worth exploring further as these bacteria are part of the 'hedgehog' consortia in the dental plaque - dynamics are relevant for oral health in general. /end

Happy to see this out! We analysed the dental #microbiome of children with #primaryimmune deficiencies underwent non-surgical therapy. Prevalence of gum disease was higher in this group and the aim was to look at longitudinal data to see if therapy modulated the microbiome. 1/

https://onlinelibrary.wiley.com/doi/10.1111/jcpe.14201

Smart! Stable isotope tracing via LC/MS metabolomics to discover unknown metabolic reactions in cells & mice. ๐Ÿงช

#teammassspec #metabolomics

https://www.nature.com/articles/s41467-025-60258-7

Charting unknown metabolic reactions by mass spectrometry-resolved stable-isotope tracing metabolomics - Nature Communications

IsoNet, an isotopologue similarity networking strategy based on mass spectrometry-resolved stable-isotope tracing metabolomics, enables ab initio elucidation of unknown metabolites and their reactions, which is applied to the glutathione metabolic reaction network.

Nature

... A. Oveta Fuller (1955-2022). Her obituary in The Lancet honors her "extensive contribution to the fight against the myths relating to HIV and COVID-19"

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00019-1/fulltext

On Wikipedia: https://en.wikipedia.org/wiki/A._Oveta_Fuller

3/3

#BlackHistoryMonth

....Jane Hinton (1919-2003).

She's the Hinton behind the Mueller-Hinton agar culture medium...

2/3

https://en.wikipedia.org/wiki/Jane_Hinton

#BlackHistoryMonth

Jane Hinton - Wikipedia

In the mood to honor accomplishments in microbiology? A trio of African-American women who made a mark, with Wikipedia pages to visit:

Ruth Ella Moore (1903-1994). In 1933, she was the 1st African-American woman to gain a PhD in natural science

https://en.wikipedia.org/wiki/Ruth_Ella_Moore

#BlackHistoryMonth

Ruth Ella Moore - Wikipedia

Have you ever been annoyed when heating your oven that it does not tell you when it is hot? there is the little red light of course but who wants to keep going to the kitchen checking that all the time!

With my very rudimentary skills I built a little device from an Arduino that monitors the oven light and sounds a buzzer when the oven is at temperature (i.e. the light turns off). More details and code etc. on my blog: https://rhizobia.nz/node/65 #Arduino

Oven light detector | NZ Rhizobia

Do I know anyone who has recently (past few years) secured a New Investigator #BBSRC Research grant? We are writing one and could really do with an example of what works..
If you do and would be willing to share all or part of the application material the #NeuroESC lab would be eternally grateful ๐Ÿ™

Edit: this is what we're applying to: https://www.ukri.org/opportunity/bbsrc-new-investigator-award-2025-round-one-responsive-mode/

Edit 2: Thanks to you all we've already got 3 example applications! You are all awesome ๐Ÿค— This will already help a lot, the last thing we would need is one from the most recent call (Jan 2024?) and as a "New Investigator", especially if you are also willing to share the reviewers' comments which are really useful to see what people look for in these applications - DM me if so ๐Ÿ™
(It's our first one... lots to learn but not so many opportunities for learning!)
#Research #ResearchFunding #ResearchGrants

BBSRC new investigator award: 2025 round one: responsive mode

Apply for funding for a research grant in any area within the remit of Biotechnology and Biological Sciences Research Council (BBSRC).