Detection of supergroup B Wolbachia strains and their co-infection with Plasmodium falciparum in wild Anopheles funestus in southeastern Tanzania: implications for malaria control.
https://pubmed.ncbi.nlm.nih.gov/41845520
Detection of supergroup B Wolbachia strains and their co-infection with Plasmodium falciparum in wild Anopheles funestus in southeastern Tanzania: implications for malaria control - PubMed
Unlike findings from the previous study, this study demonstrates that An. funestus s.l. in southeastern Tanzania are infected with Wolbachia, at a surprisingly high prevalence. This study also provides the first report on Wolbachia-P. falciparum co-infection status in An. funestus s.l. in Tanzania. …
Rapid Genomic Adaptation of Drosophila Melanogaster to Wolbachia Elimination.
https://pubmed.ncbi.nlm.nih.gov/41843121
Rapid Genomic Adaptation of Drosophila Melanogaster to Wolbachia Elimination - PubMed
Rapid Genomic Adaptation of Drosophila Melanogaster to Wolbachia Elimination
Structural reorganization and genomic context define a divergent lineage of the Wolbachia male-killing gene wmk
https://doi.org/10.64898/2026.03.16.712054
Structural reorganization and genomic context define a divergent lineage of the Wolbachia male-killing gene wmk
Patterns of diversity in symbiont effector genes provide insight into the evolutionary processes that shape their diversification, particularly those arising from host-symbiont interactions. In one of the most widespread symbiont genera, Wolbachia, the male-killing candidate gene wmk encodes a putative transcriptional regulator. Sequence divergence of this effector gene from a limited number of strains has revealed at least five phylogenetic types. However, additional wmk variants characterized by a large in-frame deletion and protein reorganization suggest that diversity in wmk extends beyond sequence variation alone. To gain further insight into wmk effector diversity, homologous proteins from 251 Wolbachia genomes were analyzed using comparative sequence and structure-informed approaches. The results show that sequence and structural diversification largely follow similar patterns; however, one lineage newly identified in this analysis stands out due to pronounced structural reorganization. The distinct genomic neighborhood of this divergent lineage, relative to other wmk lineages, suggests additional diversity at the regulatory level. Together, these findings demonstrate that variation in protein structure and genomic context complements sequence-level polymorphism in shaping wmk effector diversity in Wolbachia. Further analyses indicate that symbiont supergroup and host taxonomic order constrain the distribution of the divergent wmk lineage.
### Competing Interest Statement
The authors have declared no competing interest.
INSPIRE Programme, Department of Science and Technology, IN, DST/INSPIRE/04/2019/000478
Host-Associated Bacterial Community Changes After Laboratory Introduction Vary With Wolbachia Presence.
https://pubmed.ncbi.nlm.nih.gov/41833509
Host-Associated Bacterial Community Changes After Laboratory Introduction Vary With Wolbachia Presence - PubMed
Translocating organisms from their natural habitats to laboratories can significantly alter their microbial communities, yet this impact is often overlooked. While common in research, the effects on microbiomes and how laboratory findings relate to natural field dynamics require further study. Symbi …
Barriers and facilitators to dengue prevention strategy: a scoping review in Bangladesh and comparative analysis with other dengue-prone regions.
https://pubmed.ncbi.nlm.nih.gov/41832419
Barriers and facilitators to dengue prevention strategy: a scoping review in Bangladesh and comparative analysis with other dengue-prone regions - PubMed
Barriers and facilitators to dengue prevention strategy: a scoping review in Bangladesh and comparative analysis with other dengue-prone regions
Modelling Aedes albopictus management, incorporating immigration and bi-directional Wolbachia interactions.
https://pubmed.ncbi.nlm.nih.gov/41822118
Modelling Aedes albopictus management, incorporating immigration and bi-directional Wolbachia interactions - PubMed
The online version contains supplementary material available at 10.1007/s10340-026-02030-4.
Detection of novel Wolbachia strains in Aedes aegypti populations from a recent arbovirus outbreak region in Pune District, Maharashtra, India (2024).
https://pubmed.ncbi.nlm.nih.gov/41822129
Detection of novel Wolbachia strains in Aedes aegypti populations from a recent arbovirus outbreak region in Pune District, Maharashtra, India (2024) - PubMed
<span><i>Aedes aegypti</i> mosquitoes are principal vectors of arboviruses such as dengue, chikungunya, and Zika. The intracellular symbiont <i>Wolbachia pipientis</i> is known to inhibit viral replication and induce cytoplasmic incompatibility, making it a promising candidate for biological vector contro</span> …
16S rRNA gene-based genetic diversity of Wolbachia strains infecting Anopheles gambiae s.s. and Anopheles coluzzii in Côte d'Ivoire.
https://pubmed.ncbi.nlm.nih.gov/41802556
16S rRNA gene-based genetic diversity of Wolbachia strains infecting Anopheles gambiae s.s. and Anopheles coluzzii in Côte d'Ivoire - PubMed
Wolbachia is an endosymbiotic bacterium widely distributed among arthropods and has been reported in Anopheles gambiae s.l. Transmitted maternally, Wolbachia can manipulate host reproductive biology and has the ability to reduce or block the transmission of pathogens. This study aimed to analyze the …
Microbial communities and wing variation associated with ectoparasitic mites in medically important Mansonia mosquitoes (Diptera: Culicidae) from coconut plantation habitats in central Thailand.
https://pubmed.ncbi.nlm.nih.gov/41791635
Microbial communities and wing variation associated with ectoparasitic mites in medically important Mansonia mosquitoes (Diptera: Culicidae) from coconut plantation habitats in central Thailand - PubMed
This study presents the comprehensive assessment of the bacterial microbiome and the effects of ectoparasitic mites on wing morphometry in Mansonia mosquitoes, namely, Ma. annulifera, Ma. indiana, and Ma. uniformis from coconut-growing areas in central Thailand. High-throughput sequencing of the 16S …
Wolbachia wMel and wAlbB strains differentially impact the vector competence of Aedes aegypti with a Brazilian genetic background for DENV-1 virus.
https://pubmed.ncbi.nlm.nih.gov/41782057
Wolbachia wMel and wAlbB strains differentially impact the vector competence of Aedes aegypti with a Brazilian genetic background for DENV-1 virus - PubMed
The similar DENV-1 loads in mosquito bodies over time (7, 14, and 21 dpi) infected with either the wMel or wAlbB strain, regardless of the viral titer of the infectious blood meal, suggest that Wolbachia may have a maximum pathogen-blocking capacity beyond which additional virus suppression cannot b …
