When I learned the syllabary several years it felt like I had to unlearn the association of those glyphs with Latin lookalikes!
It's also interesting that Sequoyah's original syllabary was very squiggly and quite unlike the Latin alphabet—'twasn't 'til the problem of printing presented itself that he made the simplified, blockier script we know and love today, tweaked thereafter by Elias Boudinot and Samuel Worcester.