What a profoundly ridiculous take. We have no “ecological relationship” worth preserving with pathogenic respiratory viruses. They are parasites, not symbionts. This deadly theater of the absurd requires ever-increasing levels of suspension of disbelief. https://www.telegraph.co.uk/news/2022/12/09/lockdowns-put-us-mercy-disease/
🐦🔗: https://twitter.com/arijitchakrav/status/1603314422415515650
So #covid causes a decrease in humoral immunity. Meaning that the mucosa of the nose & throat are no longer able to fend off invaders. LIKE INVASIVE STREP A! Or flu. Or RSV! See a pattern here? Infecting kids over & over is a very BAD idea #LongCovidKids https://link.springer.com/article/10.1007/s12668-022-01020-x
🐦🔗: https://twitter.com/RogueVictorian/status/1603605756674285568
In recovered COVID-19 patients, the state of mucosal immunity remains understudied. Cytological, functional, and metabolic characteristics of neutrophils and the interleukin status will help to correctly assess the need for immunorehabilitation measures. The study objective is to assess the state of mucosal immunity after COVID-19. A comprehensive study of mucosal immunity included the assessment of nasal mucosal neutrophils with the monitoring of destructive and apoptotic changes as well as examination of the functional and metabolic activity of neutrophils entering the nasal secretions. Phagocytic activity was assessed using microbial suspension of Staphylococcus aureus, as well as intracellular oxygen-dependent biocidity, the functions of capturing, absorbing, and killing pathogens. Study of the secretory component included assessment of interleukin levels (TNF-α, IL-10, IFN-γ) and the content of sCD95 (sAPO-1/FAS), membrane marker of apoptosis, in the nasal secretions. Cell wall neutrophils in recovered COVID-19 patients show enhanced destructive and apoptotic processes within the cells. Functional disorders due to inhibited phagocytosis of autoflora are recorded. Functionally defective cells are brought into the nasal secretions; they demonstrate severely inhibited oxygen-dependent biocidity, rapid depletion of reserves, incomplete phagocytosis, and limited ability to capture pathogens, which can contribute to the growth of various pathogenic viruses and bacteria. In the nasal secretions, the concentration of sCD95 (sAPO-1/FAS), the membrane marker of apoptosis, is increased. Elevated level of pro- and anti-inflammatory cytokines (TNF-α, IL-10) downregulates IFN-γ, thus directly contributing to the formation of functionally defective neutrophils. Compensatory increase in the IL-10 anti-inflammatory cytokine under the influence of SARS-CoV-2 virus proteins downregulates IFN-γ and is a cofactor of depression of intracellular biocidity of neutrophils. An increased level of the TNF-α pro-inflammatory cytokine increases apoptotic and destructive changes in neutrophils entering the nasal secretion. Virus-induced, functional, and metabolic impairment of neutrophils of the mucosal immunity system develop in recovered COVID-19 patients, thus providing a scientific rationale for immunomodulatory therapy.
From Dr. Al-Aly’s study, people with Covid we’re more likely to get other infections afterward
Another study still in preprint found that kids who had RSV were more likely to have had Covid
In terms of public health, we are performing worse than a pre-modern society
A primitive society that does not have PCR would simply notice hospitalizations are back and would reinstate what worked
We are choosing to not use measures that we admitted lowered RSV
Geoffrey P. Johnston
Anthony J Leonardi
Peter Kalmus