🚨NEW POD ALERT 🚨
Trial of the Week: ROSE 🌹
Ft. Christina Rose
Proposed mechanism for NMBA in ARDS 🫁
ACURASYS v. ROSE ⚔️
Adjunctive therapies received 💉
Current guideline recommendations 📜
Using alternate NMBA 🤔
Favorite concerts 👅
& much more!
🟢 https://open.spotify.com/episode/2jngswtCMmWSQuyKDe3A8S?si=b66396966f084689
🚨NEW POD ALERT🚨
Rapid Reaction: BLING III
Ft. Jason Roberts
BLING research group 💎
Biggest obstacle to completing ⛰️
RCT v. SR/MA findings ⚔️
Continuous v. extended-interval 🎯
Apply these findings to all? 🤔
Future BLING III articles 📰
& much more!
https://open.spotify.com/episode/6wGSVniWautpQBKrGmW9JN?si=2eb8eaf2553c44d5
Listen to this episode from Pharmacy to Dose: The Critical Care Podcast on Spotify. Rapid Reaction: BLING III Special Guest: Jason Roberts, BPharm, PhD, FSHP 05:10 – BLING research background 17:30 – BLING III methodology/results 53:50 – Practical application/future directions Reference List: https://pharmacytodose.com/wp-content/uploads/2024/07/bling-iii-rapid-reaction-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices
🚨NEW POD ALERT🚨
ANNEXa-I Deep Dive: Part II
Ft. Scott Dietrich, Brian Gilbert, & Todd Miano
Mechanism behind thrombotic events? 🎯
Role of VTE prophylaxis? 🩸
Safely use in surgical patients? 🛑
Lab assays for DOAC? 🧑🔬
P&T “elevator pitch” 🎙️
& more!
https://open.spotify.com/episode/5sJrkZnMckytzKsIuE7qUE?si=880c7284223e4150
Listen to this episode from Pharmacy to Dose: The Critical Care Podcast on Spotify. ANNEXa-I Deep Dive Part II Special Guests: Scott Dietrich, PharmD, BCCCP Brian Gilbert, PharmD, MBA, BCCCP, FCCM, FNCS Todd Miano, PharmD, PhD, FCCM 03:13 – Safety/thrombotic findings 21:50 – Questions that remain 26:50 – Practical considerations 41:40 – P&T elevator pitch Reference List: https://pharmacytodose.com/wp-content/uploads/2024/06/annexai-deep-dive-part-ii-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices
🚨NEW POD ALERT🚨
ANNEXa-I Deep Dive: Part I
Ft. Scott Dietrich, Brian Gilbert, & Todd Miano
Why is andexanet alfa so polarizing? 🌟
Utility in anti-FXa levels? 🔎
Hemostasis v. mRS/mortality primary outcome ⚔️
Change in sample size/interim analysis p-value mid-study? 🤔
& so, so much more!
💻 (First ever full YouTube video): https://youtu.be/0hz1Ce1wQt4
🚨NEW POD ALERT🚨
Jan 2024 Literature Review Series ❄️
Ft: Haley Torr & Nick Tran
ARDS guidelines 🫁
EASE study 🧠
INCEPTION PP analysis 🫀
ASAP ECMO fluconazole dosing 🧫
Learner share day 🙌
Multiple PharmD impact studies ⭐️
& more!
🟢 https://open.spotify.com/episode/65mrrF8tPrnlyww40tVnDM?si=73d116ae168f4e76
Listen to this episode from Pharmacy to Dose: The Critical Care Podcast on Spotify. Literature Review Series January 2024 Special Guests: Haley Torr, PharmD Nick Tran, PharmD 06:55 – Featured Articles 32:55 – PAD-IS articles 37:10 – Cardiology articles 46:00 – Heme articles 51:40 – Potpourri articles 60:05 – Pharmacist-featured articles 67:30 – Sweet Emotion articles Reference List: https://pharmacytodose.com/wp-content/uploads/2024/06/jan-2024-lrs-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices
🚨NEW POD ALERT 🚨
Trial of the Week: PROWESS-SHOCK 🩸
Ft. Paul Szumita
Early controversial study results 🚩🚩🚩
Balancing efficacy and safety ⚖️
Clinical pharmacist responsibilities 📝
Lessons learned from Xigris FDA approval 📜
Is this the end of drotrecogin alfa? 🛑
90’s rap references 🎙️
& much more!
https://open.spotify.com/episode/2B2KbyFVRNZ32gx65Fppax?si=0d65540a48744f4d
https://pharmacytodose.com/2024/06/20/trial-of-the-week-prowess-shock-references/
Listen to this episode from Pharmacy to Dose: The Critical Care Podcast on Spotify. Trial of the Week: PROWESS-SHOCK Special Guest: Paul Szumita, PharmD, FCCM, FASHP, BCCCP, BCPS @paulszumita 03:30 – Background studies/Setting the scene 30:25 – PROWESS-SHOCK discussion/Where are we now Paul Szumita joins to highlight a June Trial of the Week “Drotrecogin alfa (activated) in adults with septic shock” published in the New England Journal of Medicine in 2012. To fully understand the discussion regarding drotrecogin alfa, Paul and I review the mechanism of action and its proposed action in the treatment of sepsis. Then we review earlier studies and the controversy behind the FDA approval process. Finally, we go into detail on what Clinical Pharmacists were tasked with doing at the time based on treatment protocols or hospital restrictions. Then we dive into the Trial of the Week, discussing the study design and results. What was the mood in ICUs and Pharmacy Departments after this publication? How much did our sepsis care improve from PROWESS to PROWESS-SHOCK? What lessons did we learn with the Xigris FDA approval process? Is there a patient population that could still benefit from drotrecogin alfa treatment? Plus, trial fun facts, issues with calculating APACHE II scores, and so much more. Reference list: https://pharmacytodose.com/wp-content/uploads/2024/06/prowess-shock-trial-of-the-week-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices
🚨NEW POD ALERT🚨
2023 Year-In-Review Literature Review Series
Ft: Jac Crawford & Kate Hartman
First ever Year-In-Review episode! 🥇
8 different categories 8⃣
16 total articles 🎯
All voted on by YOU, the listeners 🗳️
🟢 https://open.spotify.com/episode/6KeipGdKdynD6Lq2EKMhtd?si=08c8bc4b8a264faa
💻 https://pharmacytodose.com/2024/06/06/2023-year-in-review-literature-review-series-references/
Listen to this episode from Pharmacy to Dose: The Critical Care Podcast on Spotify. Literature Review Series 2023 Year-In-Review Special Guests: Jacquelyn Crawford, PharmD @jacuronium Kathleen Hartman, PharmD @HartKate8 04:30 – Neurology 11:05 – Cardiology 18:50 – Cardiac Arrest 26:30 – Pulmonary 35:00 – Sepsis 44:05 – Endocrine/Renal 52:30 – Trauma 61:05 – Infectious Diseases Reference List: https://pharmacytodose.com/wp-content/uploads/2024/06/yir-2023-lrs-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices
🚨NEW POD ALERT🚨
Trial of the Week: Ketamine for EM Agitation 🤬
Ft. Justin Lin, PharmD, BCPS, BCCCP
Pharmacokinetic considerations 🎯
Influence of route of administration 💉
Effective education strategies 🍪
Unexpected challenges 🛑
Droperidol-midazolam v. haloperidol-lorazepam ⚔️
& so much more!
🟢 https://open.spotify.com/episode/2zyMrdVmICfpAtc696Lmsf?si=dcb36a35f3e34435
🚨NEW POD ALERT🚨
Trial of the Week: DESIRE &
In-flight medical emergencies
Ft. Michael Liu and Jim Miller @millerjtm
Landmark dexmedetomidine articles 📰
Anti-inflammatory properties? 📉
DESIRE external validity 🎯
Which sedative would Jim and I want? 🤔
Is this Michael’s first emergency response ✈️
Advice when responding to medical emergency🚦
& much, much more!
(PS: peep the new graphic for this episode)
https://open.spotify.com/episode/2sSWlZs6Wp7eB2rPicoQlt?si=105f2b1e23024d9c
Listen to this episode from Pharmacy to Dose: The Critical Care Podcast on Spotify. Trial of the Week: DESIRE & In-Flight Medical Emergencies References Special Guests: Jim Miller, PharmD, BCCCP @millerjtm Michael Liu, PharmD, MBA, BCCCP, BCNSP, BCPS 04:05 – DESIRE trial 31:15 – In-flight medical emergencies The episode starts off with special guest, Jim Miller, helping review the DESIRE study as a Trial of the Week. We set the scene reviewing dexmedetomidine pharmacokinetic advantages and landmark dexmedetomidine research. Then we highlight the DESIRE trial itself discussing the study methodology and results. What was considered usual care with regards to sedation? What is the external validity in this trial? What was the effect of changing the primary outcome measure mid-study? Are there anti-inflammatory properties with dexmedetomidine? What did Jim’s novel research show? What would Jim and I want for sedation if mechanically ventilated? And much more. Then the episode closes with Michael Liu highlighting his experience assisting with an in-flight medical emergency. We review his AJHP article describing his experience. Was this his first time in this situation? Biggest difference between in-hospital and out-of-hospital emergency response? What advice would he give others? And so much more. Reference list: https://pharmacytodose.files.wordpress.com/2024/05/desire-trial-of-the-week-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices
