Simultaneous single-cell analysis of 5mC and 5hmC with SIMPLE-seq - Nature Biotechnology

SIMPLE-seq measures both 5-methylcytosine and 5-hydroxymethylcytosine at base resolution in single cells.

An oncolytic virus–T cell chimera for cancer immunotherapy - Nature Biotechnology

Oncolytic adenovirus is delivered on T cells and engineered to express a checkpoint inhibitor.

Author Correction: Prime editing using CRISPR-Cas12a and circular RNAs in human cells - Nature Biotechnology

Author Correction: Predicting the efficiency of prime editing guide RNAs in human cells - Nature Biotechnology

Efficient prime editing in two-cell mouse embryos using PEmbryo - Nature Biotechnology

Prime editing is used to efficiently edit early-stage mouse embryos with few on-target byproducts.

Simultaneous nanopore profiling of mRNA m6A and pseudouridine reveals translation coordination - Nature Biotechnology

A machine learning pipeline for nanopore sequencing analyzes m6A and Ψ simultaneously.