Hell yeah! Your daughter is a crunchy-gamer in the making! I can relate to her in the sense of her wanting to play things with a solid structure that she can study and master, to keep her engaged. I think that she will enjoy Savage Worlds.
If 5e is rules-heavy, then SWADE is a rules-medium system. The slowest part is making a character because the system is universal and there are a ton of options, but as a DM, you can curate the options for your players. Also, there are Savage Settings and one of them is "East Texas University." Teens will be able to relate to the school setting but "rad-idfied". They get to role play as university students who then solve mysteries, join fraternities, hunt monsters, drive and modify badass combat cars, etc.
Also, maybe it’s time to introduce the kids to Cyberpunk RED. It’s not hard to learn or teach and the game itself is fairly lightweight.
Otherwise, for the smaller, Index Card RPG or EZD6 can work. Both are super streamlined and they retain that D&D feeling. Also, games using the LUMEN system can give the kids a nice dopamine rush. The creator basically states that his system is meant to make players feel like Overwatch or Diablo characters. In contrast with 5e, in which players often hoard spells and powers for the "right event", LUMEN makes everyone use their spells and special skills all the time in fast paced combat that resolves super quick. Check out ”Nova" and "Light".
And personally I don’t like them, but you can also show them the FATE and Ironsworn/Starforged systems to broaden their horizons and make them experience a different perspective which they might love.