Noticing that people replying to other people I don't follow are showing up in my local timeline. So now I'm worrying: every time I have a conversation with someone, am I polluting everyone else's timeline with an unending series of replies?

That was one thing "the bird site" got right: you didn't see peoples' replies to people unless you followed both of them.

@csilverman you can set it so only the people you mentioned can see it (or set it to private, in which case you can set it so only followers can see it)
@kuro heh, just had that pointed out to me. Good to know.