People with the autoimmune disease systemic lupus erythematosus are known to have an altered gut microbiome. *Faecalibacterium prausnitzii* abundance is depressed. A mouse study finds that supplemental *F. prausnitzii* changed the gut microbiome and reduced the symptoms of lupus.
Summary: https://medicalxpress.com/news/2026-06-potential-probiotic-treatment-lupus.html
Original paper: https://www.nature.com/articles/s41467-026-71718-z

First potential probiotic treatment for lupus identified by researchers
Scientists at UT Health San Antonio, the academic health center of The University of Texas at San Antonio, have found a link between a bacterium in the gut microbiome (ecosystem) and lupus that could lead to more effective treatment of the disease, described in a study published in Nature Communications.