Redish Lab5d ago

New #elife paper dropped:

C. C. Damphousse, O. L. Calvin, A. D. Redish (2026) Hippocampal representations differentiate reactive and anticipatory responses during foraging under threat. eLife. 15:RP111762
https://doi.org/10.7554/eLife.111762.1

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Hippocampal representations differentiate reactive and anticipatory responses during foraging under threat

Show threadRedish Lab5d ago

https://doi.org/10.7554/eLife.111762.1

We put rats into an approach-avoidance conflict by training them to run a linear track to get food and then put a robot predator between the nest and the food.

Is it safe to run the gauntlet?

Fun fact - it was the googly eyes that made the difference. :)

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Hippocampal representations differentiate reactive and anticipatory responses during foraging under threat

Show threadRedish Lab

https://doi.org/10.7554/eLife.111762.1

We find three very interesting behaviors - "retreats" from actual attack, "mid-track aborts" --- fleeing from worry, and "mid-track continues" --- hesitation on the track followed by continuing on into the danger...

Decoding dorsal hippocampus representations finds these three behaviors entail fundamentally different representations.

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Hippocampal representations differentiate reactive and anticipatory responses during foraging under threat

Jun 15 at 11:05pmWeb