Firefox has added WebSerial support in 151. This is useful for cloudless communication with #embedded devices.
Rather than using the polyfill (https://github.com/kuba2k2/firefox-webserial) that requires cumbersome installation of a native binary, this has all the native code shipped, but seems to require a (presumably trivial) extension per site that uses it due to browsers' sad habit of taking blame for already vulnerable setups.
Looking forward to trying it out, and hoping for WebBluetoot and WebUSB to be next.
GitHub - kuba2k2/firefox-webserial: WebSerial API Polyfill for Mozilla Firefox browser

WebSerial API Polyfill for Mozilla Firefox browser - kuba2k2/firefox-webserial

GitHub
It's even better than expected – while technically there might be an add-on involved, this Just Works:
- Go to any #WebSerial page, eg. https://youseetoo.github.io/indexWebSerialTest.html (picked as example because it's 4y old and certainly made no adjustments to Firefox)
- Popup says "This site is requesting access to … not guaranteed to be safe. Only continue if you trust this site." / "Continue to Installation"
- Another popup "This add-on gives ${DOMAIN} access to your serial devices." / "Add"
- Port selection popup!
openUC2 WebSERIAL Demonstration

WebSerial + WebRTC + UC2 demo