@evan No, not in general. But it highly depends on what the application does.

is a keyboard and mouse better than a touchscreen?
for a text editor, yeah! but for a drawing application, I'd rather take the touch screen (or a pen).
for like, a wifi menu? it shouldn't really matter. both work just as well and it's mostly a personal preference.
for a first person shooter? you could argue either way, but don't forget that lots of folks love joypads/controllers.

for a text editor, i'd much rather have a GUI than a CLI (like ed). but a lot of people prefer a TUI (like nano).
for file management, it doesn't really matter. most people know how to use a GUI, lots of them even have a lot of shortcuts and tricks. but nothing beats the inline scripting of a CLI for flexibility (and again, some people swear by a TUI, like ranger).
for a patchbay graph (like crosspipe), I feel like a GUI is infinitely better than a CLI. you could implement the same operations in CLI, but it would not be the same category of application.
for something like ffmpeg? it has a bazillion switches that would be incredibly overwhelming to present in a WYSIWYG-GUI style. it's difficult to make it anything but a CLI. arguably, the CLI sucks too, but at least you can copy paste magic incantations instead of needing to follow a tutorial with twelve screenshots on exactly where to click.