#PlantScienceClassics #20: Kinetin & Cytokinins. In 1955 Carlos Miller, Folke Skoog & co-workers describe the first #Cytokinin and its role in promoting cell division and growth promotion. #Phytohormones #PlantScience #PlantDevelopment pubs.acs.org/doi/abs/10.1... pubs.acs.org/doi/abs/10.1...
Folke Skoog’s career in phytohormone research started in 1930 as undergrad at @[email protected], when he expressed his interest in #PlantBiochemistry to his mentor Carl Lindegren. Lindegren suggested Herman Dolk as supervisor for Skoog in what can best be described as a half-hearted endorsement (image).
Dolk studied with auxin pioneer Friedrich Went @[email protected], but Skoog's time with him was cut short when Dolk passed away. His place was taken by another student of Went, his son Frits-the discoverer of #auxin. It was Went who speculated that there must be a second growth factor.
While this started Skoog's mission to identify this 2nd factor, he interrupted his search for a postdoc with Dennis Hoagland, a pioneer in #PlantNutrition who was first to formulate a growth solution with exact nutrients: the now famous Hoagland solution. The second important mentor for Skoog.
His time with Went & Hoagland imprinted in Skoog an interest in hormonal growth regulation, and a sense for the importance of plant nutrition and exactly controlled growth conditions. Another scientist, Philip White, delivered the 'tool' he needed for his research: A Nicotiana callus cell culture.
White was also interested in growth regulation, but he insisted that his callus culture was completely auxin-free, and that plant growth regulation was auxin-independent. He didn't believe that auxin, or its described effects, were real - A view shared by many American scientists at the time.
When Frits Went once failed to demonstrate the effect of auxin at an AAAS meeting, it was White who loudly declared “that the auxin business was obviously a hoax and that it was high time that these charlatans from Europe were sent back to where they belonged”. An experience that shook Went.