Regret being endlessly cruel (3)

direction: down
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Source: Times Quick Cryptic No 1469 https://times-xwd-times.livejournal.com/2228352.html

See replies for a hint, the answer, and an explanation

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R_E

[this post gives you every second letter of the answer to help you solve the clue]

RUE

[this post gives you the answer without any explanation to help you interpret the clue by yourself]

RUE

Explanation:

[C]RUE[L]

Endlessly cruel = CRUEL with each end removed
Regret = RUE

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