There’s some place in Africa where, if you are talking only about humans, there may be people that is not descendent of immigrants. AFAIK nobody even knows where it is.

Neanderthal and Denisovan genes are found in all living non-Africa populations

Source:

australian.museum/…/when-and-where-did-our-specie…

When and where did our species originate?

Our species, <i>Homo sapiens</i>, has now spread to all parts of the world but it's generally believed that we originated in Africa by about 200,000 years ago. We interacted with local archaic human populations as we colonised the globe.

The Australian Museum