NCPE’s perioperative pembrolizumab position shows the bottleneck: cost-effectiveness under uncertainty when indirect evidence informs decisions.

https://www.mattheneus.com/editorial/ncpe-pembrolizumab-hta24013-perioperative-nsclc-cost-effectiveness-gap-2026-03-10

#HTA #NMA #EvidenceSynthesis #Pharma

NCPE sets a conditional reimbursement path for perioperative pembrolizumab in resectable NSCLC

On 10 March 2026, the National Centre for Pharmacoeconomics recommended perioperative pembrolizumab in resectable high-risk NSCLC be considered for reimbursement if cost-effectiveness improves, citing strong direct trial evidence versus chemotherapy and uncertain indirect comparative estimates versus nivolumab-based care.

AbangeLabs Editorial