Medetomidine has been popping up in pdx supply. What you need to know..

Withdrawal from medetomidine can occur within hours and is characterized by severe hypertension (>200 mmHg), tachycardia (>140 bpm), tremors, nausea, vomiting, agitation, and reduced mentation. (I can't empathize enough how severe, painful, awful, and fast occurring the withdrawls are!)

Medetomidine is a strong sedative that is used in veterinary settings, though it is much stronger than Xylazine. ( I should mention that unlike Xylazine, necrotic wounds have not been mentioned as a side effect of long term use)

With medetomidine, your pass out rather than nod off (not a pleasant high). During an overdose naloxone will work, however, the indiv will remain unconscious! So, consistent monitoring of breathing is necessary.